赵新湖;包海鹰;

• 1:吉林农业大学中药材学院
• 2:吉林农业大学教育部食药用菌工程中心

摘要(Abstract)：

以大黄水煎剂建立小鼠胃肠功能损害模型,探讨云芝提取物和其中的白桦脂酸对小鼠胃肠功能的影响以及白桦脂酸对小鼠在脂质过氧化方面的影响。研究结果表明云芝提取物和白桦脂酸能够较为显著地提高胃蛋白酶活性,增加胃泌素和胃酸分泌量(P<0.01);同时白桦脂酸高低剂量组能够明显降低小鼠血浆中丙二醛的含量,提高超氧化物歧化酶、谷胱甘肽过氧化物酶的活性以及肝脏匀浆中谷胱甘肽过氧化物的含量(P<0.01)。说明云芝提取物和白桦脂酸能够有效地改善小鼠的胃肠功能,且抗脂质过氧化是云芝活性成分白桦脂酸治疗作用机制之一。

关键词(KeyWords)： 云芝;白桦脂酸;胃肠功能;脂质过氧化

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 赵新湖;包海鹰;

DOI: 10.13346/j.mycosystema.150006

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